GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs6715284 | 1 | rs72934944 | chr2:202190610 | PPIL3 | chr2:201735680-201753999:- | -0.5 | -4.89 | 1.5E-6 | Rheumatoid arthritis |
| BLCA | cis | rs6715284 | 1 | rs72934960 | chr2:202204749 | PPIL3 | chr2:201735680-201753999:- | -0.44 | -3.89 | 0.000117 | Rheumatoid arthritis |
| BLCA | cis | rs6715284 | 1 | rs72934973 | chr2:202213934 | PPIL3 | chr2:201735680-201753999:- | -0.44 | -3.88 | 0.000125 | Rheumatoid arthritis |
| BLCA | cis | rs6715284 | 1 | rs72934999 | chr2:202223524 | PPIL3 | chr2:201735680-201753999:- | -0.44 | -4.14 | 4.27E-5 | Rheumatoid arthritis |
| BLCA | cis | rs6715284 | 1 | rs72937106 | chr2:202225520 | PPIL3 | chr2:201735680-201753999:- | -0.44 | -4.14 | 4.27E-5 | Rheumatoid arthritis |
| BLCA | cis | rs6715284 | 1 | rs72937118 | chr2:202229527 | PPIL3 | chr2:201735680-201753999:- | -0.44 | -4.14 | 4.27E-5 | Rheumatoid arthritis |
| BLCA | cis | rs6715284 | 1 | rs72937120 | chr2:202232611 | PPIL3 | chr2:201735680-201753999:- | -0.44 | -4 | 7.67E-5 | Rheumatoid arthritis |
| BLCA | cis | rs9815354 | 1 | rs73069392 | chr3:41787009 | ULK4 | chr3:41288091-42003660:- | 0.61 | 9.06 | 6.68E-18 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73069394 | chr3:41787233 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.53 | 1.83E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73069396 | chr3:41787236 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.53 | 1.83E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73071329 | chr3:41810539 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.57 | 1.39E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73077367 | chr3:41851959 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.88 | 1.13E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73079316 | chr3:41863859 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.53 | 1.84E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73079321 | chr3:41863910 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.63 | 8.26E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs73081353 | chr3:41906448 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.5 | 2.29E-19 | Diastolic blood pressure |